Intermediates

2-(4-ethoxybenzyl)-4-bromo-1-chlorobenzene

M.F.: C15H14BrClO
Mol. Wt.: 325.63
461432-23-5
Key starting material for the preparation of Dapagliflozin
In-house
Complete

(5-bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone

M.F.: C15H12BrClO2
Mol. Wt.: 339.61
461432-22-4
Key starting material for the preparation of Dapagliflozin
In-house
Complete

[3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride]

M.F.: C6H8ClF3N4
Mol. Wt.: 228.6
762240-92-6
It’s an sitagliptin pharmaceutical intermediate for the preparation of Sitagliptin phosphate
In-house
Complete

(2-Chloro-5-iodophenyl)(4-
fluorophenyl)methanone

M.F.: C13H7ClFIO
Mol. Wt.: 360.55
915095-86-2
Key starting material for the preparation of Empagliflozin

Under Development

2-(4-ethoxybenzyl)-1-chloro-4-iodobenzene

M.F.: C15H14ClIO
Mol. Wt.: 372.63
1103738-29-9
Key starting material for the preparation of Dapagliflozin
Under Development

(2-chloro-5-iodophenyl)(4-ethoxyphenyl)methanone

M.F.: C15H12ClIO2
Mol. Wt.: 386.61
1103738-26-6
Key starting material for the preparation of Dapagliflozin

Under Development

2-(5-iodo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene

M.F.:C18H14FIS
Mol. Wt.: 408.27
898566-17-1
Key starting material for the preparation of Canagliflozin
Under Development

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Sl.

Product Name

Structure

Molecule details

Cas. No.

Remarks/Uses

Specification

Status

1

2-(4-ethoxybenzyl)-4-bromo-1-chlorobenzene
 

M.F.: C15H14BrClO
Mol. Wt.: 325.63

461432-23-5

Key starting material for the preparation of Dapagliflozin
 

In-House

Commercial

2

(5-bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone

M.F.: C15H12BrClO2
Mol. Wt.: 339.61

461432-22-4

Key starting material for the preparation of Dapagliflozin
 

In-House

Commercial

3

(3R,4S,5R,6R)-3,4,5-tris(trimethylsilyloxy)-6-((trimethylsilyloxy)methyl)-tetrahydropyran-2-one

M.F.: C18H42O6Si4

Mol. Wt.: 466.86

32384-65-9

Uses: It’s a silylated derivative of D-gluconolactone, an intermediate for the preparation of Dapagliflozin, Empagliflozin and Canagliflozin

In-House

Commercial

4

Tafamidis

M.F.: C14H7Cl2NO3

Mol. Wt.: 308.12 g/mol

951395-08-7

Uses: Tafamidis is a key transthyretin (TTR) stabilizer used in the treatment of transthyretin-mediated amyloidosis (ATTR). Its high-purity synthesis is essential due to the molecule’s sensitivity and therapeutic significance, making it a critical API in the rare-disease segment.

In-House

Commercial

5

1-(2,5-Dimethylphenyl)-2-aminoethanol Hydrochloride

M.F.: C10H16ClNO3

Mol. Wt.: 233.69

60407-53-6

Uses: Its an intermediate for the preparation of Midodrine, Midodrine hydrochloride

Under Development

6

2-Amino-1-(2,5-dimethoxyphenyl) ethanol

M.F.: C10H15NO3

Mol. Wt.: 197.23 g/mol

3600-87-1

Uses: 2-Amino-1-(2,5-dimethoxyphenyl)ethanol is an essential advanced intermediate in the synthesis of Midodrine Hydrochloride, a well-established α₁-adrenergic agonist used for the treatment of orthostatic hypotension.

In-House

Under Development

2-(4-ethoxybenzyl)-4-bromo-1-chlorobenzene

M.F.: C15H14BrClO
Mol. Wt.: 325.63

461432-23-5

Key starting material for the preparation of Dapagliflozin

Complete

 
(5-bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone

M.F.: C15H12BrClO2
Mol. Wt.: 339.61

461432-22-4

Key starting material for the preparation of Dapagliflozin

Complete

[3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride]

M.F.: C6H8ClF3N4
Mol. Wt.: 228.6

762240-92-6

It’s an sitagliptin pharmaceutical intermediate for the preparation of Sitagliptin phosphate

Complete

(2-Chloro-5-iodophenyl)(4-fluorophenyl)methanone

M.F.: C13H7ClFIO
Mol. Wt.: 360.55

915095-86-2

Key starting material for the preparation of Empagliflozin

Under Development

2-(4-ethoxybenzyl)-1-chloro-4-iodobenzene

M.F.: C15H14ClIO
Mol. Wt.: 372.63

1103738-29-9

Key starting material for the preparation of Dapagliflozin

Under Development

(2-chloro-5-iodophenyl)(4-ethoxyphenyl)methanone

M.F.: C15H12ClIO2
Mol. Wt.: 386.61

1103738-26-6

Key starting material for the preparation of Dapagliflozin

Under Development

2-(5-iodo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene

M.F.:C18H14FIS
Mol. Wt.: 408.27

898566-17-1

Key starting material for the preparation of Canagliflozin

Under Development

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